Clean Living
Do you guys remember that time I did an IVF cycle? Remember the deal was that we would do IVF and then test the embryos to make sure they were not carrying the killer versions of Steve's genetic peculiarity? And then we would transfer the good ones only and I would get pregnant and we would live happily ever after? Except remember how I miscarried again and it turned out that the PGD-approved embryo had, indeed, carried the unbalanced translocation? Remember that? Well, I would not blame you if you don't because frankly it was forever ago (practically Cruise-Kidman, or at least Cruise-Cruz; not the Very Now Cruise-Holmes Epoch) but I bring it up because I heard from the IVF clinic today.
I had sent them a copy of the fetal karyotype and then they requested a copy of Steve's karyotype and then they needed the actual slides for both. So they looked at the one and they looked at the other and then they looked at what they had tested and they finally called to tell me: it wasn't their fault. The cell they did PGD on was normal. A few of the cells in the fetal tissue were normal. Thus, they concluded, it must have been an example of that mosaicism you read about all the time. That rare instance in which an embryo has both normal and abnormal cells (odds of occurence with PGD roughly 5-10%, are we the luckiest people you know or what?)
This is what they said and it is all very good and well, but work with me here. You start with one sperm and one egg, right? And that sperm carried an unbalanced arrangement of Steve's specific translocation. So how, exactly, were normal daughter cells (ha! daughter cells!) created from this? Anyone? Anyone? Bueller?
But, whatever. "Mosaic" is a perfectly good way of saying "unknown" as far as I am concerned.
The big news is this. My RE offered to let us do another cycle with PGD (whenever we want) and pay {ed. I am taking out the specific reduction because it just occurred to me that I should} less. And while it is not often that the generosity of an infertility clinic moves me to say, "Well done, lads" I have to admit that I am impressed.
They felt so badly about the miscarriage (correction: they felt so badly about the failure of preimplantation genetic diagnosis to succesfully identify the specified translocation) that they have given me an IVF Gift Certificate with no expiration date. Isn't that thoughtful?
Since I still (STILL) have not started a new cycle (seven weeks...) following the D&C it is all academic at this point, but it is nice to know we have it as an option, don't you think?
Tomorrow I dust off the ol' mailbag and answer leftover questions. I remember baking soda, blowjobs and blogging came up and I will check to see what else there was recently. Feel free to add anything you're curious about. We aim to please.